Certificate of Analysis
| Product Name: | HKI-357 |
| Catalog Number: | M56426 |
| CAS Number: | 848133-17-5 |
Physical and Chemical Properties
| Formula: | C31H29ClFN5O3 |
| Molecular Weight: | 574.05 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL |
| Storage: | Powder -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 with IC50s of 34 nM and 33 nM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |