Certificate of Analysis
| Product Name: | HJM-561 |
| Catalog Number: | M45356 |
| CAS Number: | 2570251-68-0 |
Physical and Chemical Properties
| Formula: | C45H51ClN9O5P |
| Molecular Weight: | 864.37 |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | HJM-561 is a potent, selective, orally bioavailable EGFR PROTAC.HJM-561 preserves the activity of cells expressing wild EGFR, and a mouse model shows inhibition of 19del//T790M/C797S, overcoming Osimertinib resistance. Possesses anti-tumor activity. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |