Certificate of Analysis

 

Product Name: HDACs/mTOR Inhibitor 1
Catalog Number: M13675
CAS Number: 2271413-06-8

Physical and Chemical Properties
Molecular Weight: 566.65
Solubility: DMSO 32.5 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: HDACs/mTOR Inhibitor 1 Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: HDACs/mTOR Inhibitor 1 is a dual Histone Deacetylases (HDACs) and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies, with IC50s of 0.19 nM, 1.8 nM, 1.2 nM and >500 nM for HDAC1, HDAC6, mTOR and PI3Kα, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.