Certificate of Analysis

 

Product Name: Guselkumab
Catalog Number: M24620
CAS Number: 1350289-85-8

Physical and Chemical Properties
Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
Analytical Data
QC Standard: ≥98.0%
H-NMR: Consistent with structure
Product Information
Description: Guselkumab is a recombinant human IgG1 monoclonal antibody against the IL-23p19 subunit. Guselkumab binds to human and cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab inhibits production of cytokines lying downstream of the IL-23 signaling pathway and can be used for psoriatic arthritis research.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.