Certificate of Analysis

 

Product Name: Gusacitinib hydrochloride
Catalog Number: M41700
CAS Number: 2228989-14-6

Physical and Chemical Properties
Formula: C24H29ClN8O2
Molecular Weight: 496.99
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Gusacitinib hydrochloride Structure
Analytical Data
QC Standard:
H-NMR: Consistent with structure
Product Information
Description: Gusacitinib (ASN-002) hydrochloride is an orally active dual SYK/JAK kinase inhibitor with IC50 values of 5, 46, 4, 11 and 8 nM for SYK, JAK1, JAK2, JAK3 and TYK2, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.