Certificate of Analysis
| Product Name: | Guanosine 3′,5′-cyclic monophosphate |
| Catalog Number: | M55306 |
| CAS Number: | 7665-99-8 |
Physical and Chemical Properties
| Formula: | C10H12N5O7P |
| Molecular Weight: | 345.21 |
| Solubility: | 0.2 M NaHCO3: 50 mg/mL |
| Storage: | -20°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.74% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Guanosine 3′,5′-cyclic monophosphate (cGMP) acts as an important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |