Certificate of Analysis
| Product Name: | GSK690693 |
| Catalog Number: | M1789 |
| CAS Number: | 937174-76-0 |
Physical and Chemical Properties
| Formula: | C21H27N7O3 |
| Molecular Weight: | 425.48 |
| Solubility: | DMSO 26 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 98.72% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | GSK690693 is a potent Akt inhibitor (Akt1 IC50 = 2 nM, Akt2 IC50 = 13 nM, Akt3 IC50 = 9 nM) which also inhibited the phosphorylation of the downstream target GSK3b in cells. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |