Certificate of Analysis


Product Name: GSK3368715 2HCl
Catalog Number: M10637
CAS Number: 1628925-77-8

Physical and Chemical Properties
Formula: C20H40Cl2N4O2
Molecular Weight: 439.46
Solubility: DMSO ≥ 100 mg/mL; Water ≥ 90 mg/mL
Storage: 2-8°C, dry, sealed
Chemical Structure: GSK3368715 2HCl Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: GSK3368715 2HCl is a novel potent, orally active, reversible type I protein arginine methyltransferases (PRMTs) inhibitor, with IC50 values of 3.1 nM, 48 nM, 1148 nM, 5.7 nM and 1.7 nM for PRMT1, PRMT3, PRMT4, PRMT6, PRMT8, respectively.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.