Certificate of Analysis
| Product Name: | GSK3-IN-3 |
| Catalog Number: | M29929 |
| CAS Number: | 331963-27-0 |
Physical and Chemical Properties
| Formula: | C24H35N3O4 |
| Molecular Weight: | 429.55 |
| Form: | Solid |
| Solubility: | DMSO 4.17 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage: | Powder -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | GSK3-IN-3 is a mitophagy inducer, inducing Parkin-dependent mitophagy. GSK3-IN-3 is also a GSK-3 inhibitor with an IC50 value of 3.01 μM. GSK3-IN-3 is non-ATP nor substrate competitive and is neuroprotective against 6-OHDA. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |