Certificate of Analysis
| Product Name: | GSK143 dihydrochloride |
| Catalog Number: | M57216 |
| CAS Number: | 2341796-81-2 |
Physical and Chemical Properties
| Formula: | C17H24Cl2N6O2 |
| Molecular Weight: | 415.32 |
| Form: | Solid |
| Solubility: | Water 100 mg/mL; DMSO ≥ 50 mg/mL |
| Storage: | 4°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | GSK143 dihydrochloride is an orally active and highly selective spleen tyrosine kinase (SYK) inhibitor with a pIC50 of 7.5. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |