Certificate of Analysis
| Product Name: | GSK-A1 |
| Catalog Number: | M28374 |
| CAS Number: | 1416334-69-4 |
Physical and Chemical Properties
| Formula: | C29H27FN6O4S |
| Molecular Weight: | 574.63 |
| Form: | Solid |
| Storage: | Powder -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥98.5% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | GSK-A1 is a selective type III phosphatidylinositol 4-kinase PI4KA (PI4KIIIα) inhibitor with a pIC50 of 8.5-9.8. GSK-A1 inhibits PtdIns(4,5)P2 resynthesis with an IC50 of about 3 nM. GSK-A1 potently decreases the levels of PtdIns(4)P with a negligible effect on PtdIns(4,5)P2. GSK-A1 has the potential for anti-hepatitis C virus (HCV) research. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |