Certificate of Analysis

 

Product Name: GNE-617 hydrochloride
Catalog Number: M14476
CAS Number: 2070014-99-0

Physical and Chemical Properties
Molecular Weight: 463.88
Solubility: DMSO 5.56 mg/mL (ultrasonic and warming and heat to 60°C)
Storage: 2-8°C, dry, sealed
Chemical Structure: GNE-617 hydrochloride Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: GNE-617 hydrochloride is a specific NAMPT inhibitor that inhibits the biochemical activity of NAMPT with an IC50 of 5 nM and exhibits efficacy in xenograft models of cancer.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.