Certificate of Analysis
| Product Name: | Glembatumumab vedotin |
| Catalog Number: | M58984 |
| CAS Number: | 1182215-65-1 |
Physical and Chemical Properties
| Solubility: | For Powder, reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. |
| Storage: | Store at ≤ -20℃ for up to 24 months. Avoid repeated freeze-thaw cycles. |
Analytical Data
| QC Standard: | >99%, Endotoxin < 1 EU/µg |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Glembatumumab vedotin (CDX-011) is an antibody-drug conjugate (ADC) comprising a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB) and conjugated to the potent tubulinbinding cytotoxic agent MMAE via a protease-sensitive vc linker. Glembatumumab vedotin has potent anticancer effects. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |