Certificate of Analysis
| Product Name: | Givosiran |
| Catalog Number: | M40953 |
| CAS Number: | 1639325-43-1 |
Physical and Chemical Properties
| Molecular Weight: | 16300.6 |
| Form: | Solid |
| Storage: | -20°C, protect from light |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Givosiran is a small interfering RNA that targets hepatic aminofibrillar synthase 1 (ALAS1) messenger RNA, down-regulates ALAS1 mRNA, and prevents the accumulation of neurotoxic α-aminofibrillar acids and porphyrins, which can be used in porphyria-related studies. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |