Certificate of Analysis


Catalog Number: M11442
Product Name: GDC-6036
CAS Number: 2417987-45-0

Physical and Chemical Properties
Formula: C29H32ClF4N7O2
Molecular Weight: 622.06
Solubility: N/A
Storage: at -20°C
Chemical Structure: GDC-6036  Structure
Analytical Data
HPLC: Shows Min purity
H-NMR: Consistent with structure
Product Information
Description: Gdc-6036 (compound 17A) is an oral covalently mutated KRAS G12C inhibitor with IC50<0.01 μM against K-Ras G12C. The EC50 of GDC-6036 in K-Ras G12C-alkylated HCC1171 cells was 2 nM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.