Certificate of Analysis

 

Product Name: GDC-2992
Catalog Number: M58665
CAS Number: 2753651-10-2

Physical and Chemical Properties
Formula: C45H51ClN8O5
Molecular Weight: 819.39
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: GDC-2992 Structure
Analytical Data
QC Standard:
H-NMR: Consistent with structure
Product Information
Description: GDC-2992 is an orally active androgen receptor (AR) degrader. GDC-2992 degrads AR with a DC50 value of 2.7 nM and inhibits proliferation with an IC50 valude of 9.7 nM in VCaPcells.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.