Certificate of Analysis
| Product Name: | Sobetirome |
| Catalog Number: | M6746 |
| CAS Number: | 211110-63-3 |
Physical and Chemical Properties
| Formula: | C20H24O4 |
| Molecular Weight: | 328.4 |
| Form: | Solid |
| Solubility: | DMSO ≥ 60 mg/mL |
| Storage: | -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Sobetirome is a thyroxine mimetic and a high affinity agonist for the thyroid hormone receptors THR-β and THR-α (KD values 67 and 440 pM, respectively). The in vitro effects on TRα1 and TRβ1 receptors are 5 and 100 times stronger than those of the endogenous agonist T3, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |