Certificate of Analysis

 

Product Name: Gardiquimod diTFA 
Catalog Number: M27867
CAS Number: 1159840-61-5

Physical and Chemical Properties
Formula: C21H25F6N5O5
Molecular Weight: 541.44
Form: Solid
Solubility: DMSO 50 mg/mL (ultrasonic); Water 25 mg/mL (ultrasonic)
Storage: 4°C, dry, sealed
Chemical Structure: Gardiquimod diTFA  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: Gardiquimod diTFA, an imidazoquinoline analog, is a TLR7/8 agonist. Gardiquimod diTFA could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod diTFA specifically activates TLR7 when used at concentrations below 10 μM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.