Certificate of Analysis

 

Catalog Number: M1712
Product Name: FTY720 hydrochloride
CAS Number: 162359-56-0

Physical and Chemical Properties
Formula: C19H33NO2.HCl
Molecular Weight: 343.9
Solubility: DMSO 60 mg/mL
Storage: at -20°C
Chemical Structure: FTY720 hydrochloride Structure
Analytical Data
HPLC: Shows Min 99.46% purity
H-NMR: Consistent with structure
Product Information
Description: Fingolimod (FTY720) HCl is a 1-phospho-neuraminol S1P receptor antagonist with an IC50 of 0.33 nM. , FTY720 can dephosphorylate AMPK by activating PP2A and reduce the expression level of phosphorylated eEF2K, ultimately leading to ADCD and iron death in human multiple myeloma cells.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.