Certificate of Analysis

 

Product Name: FKBP12 PROTAC dTAG-7
Catalog Number: M29153
CAS Number: 2064175-32-0

Physical and Chemical Properties
Formula: C63H79N5O19
Molecular Weight: 1210.32
Form: Solid
Solubility: DMSO 150 mg/mL (ultrasonic)
Storage: -20°C, dry, sealed
Chemical Structure: FKBP12 PROTAC dTAG-7 Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional degrader. FKBP12 PROTAC dTAG-7 (dTAG-7) is a degrader of FKBP12F36V with expression of FKBP12F36V in-frame with a protein of interest. FKBP12 PROTAC dTAG-7 (dTAG-7) also is a selective degrader of BET bromodomain transcriptional co-activator BRD4 by bridging BET bromodomains to an E3 ubiquitin ligase CRBN.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.