Certificate of Analysis

 

Product Name: Feniralstat 
Catalog Number: M29315
CAS Number: 2166320-76-7

Physical and Chemical Properties
Formula: C26H25F2N5O4
Molecular Weight: 509.5
Form: Solid
Solubility: DMSO 100 mg/mL (ultrasonic and warming and heat to 60°C)
Storage: Powder -20°C
Chemical Structure: Feniralstat  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: Feniralstat (compound 30), a pyrazole derivative, is a potent kallikrein inhibitor with an IC50 of 6.7 nM for Human plasma kallikrein (pKal). Feniralstat has no inhibition on Human KLKl, Human FXIa, Human Factor Xlla (all IC50>40 μM).
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.