Certificate of Analysis
| Product Name: | NLX-101 (F-15599) |
| Catalog Number: | M10608 |
| CAS Number: | 635323-95-4 |
Physical and Chemical Properties
| Formula: | C19H21ClF2N4O |
| Molecular Weight: | 394.85 |
| Solubility: | DMSO ≥ 90 mg/mL |
| Storage: | 2-8°C, protect from light, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | NLX-101 (F-15599) is a highly selective G-protein biased 5-HT1A receptor agonist, with Ki of 3.4 nM. NLX-101 (F-15599) mediates antidepressant-like activity in rats via prefrontal cortex 5-HT 1A receptors. NLX-101 (F-15599) has over 1000-fold higher affinity for this target over other receptors. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |