Certificate of Analysis
| Product Name: | Evolocumab |
| Catalog Number: | M1595 |
| CAS Number: | 1256937-27-5 |
Physical and Chemical Properties
| Formula: | C6242H9648N1668O1996S56 |
| Molecular Weight: | 141788.63 |
| Storage: | -80°C for long term |
Analytical Data
| QC Standard: | >98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Evolocumab (AMG 145) is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9). Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |