Certificate of Analysis
| Product Name: | Etrolizumab |
| Catalog Number: | M24543 |
| CAS Number: | 1044758-60-2 |
Physical and Chemical Properties
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Etrolizumab (rhuMAb Beta7) is a gut-selective, anti-β7 integrin monoclonal antibody. Etrolizumab is specific targeting of the β7 subunit of α4β7 and αEβ7 integrins with Ki values of 18 nM and 1800 pM for Human α4β7 and Human αEβ7-293, respectively. Etrolizumab can be used in research of inflammatory bowel disease (IBD). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |