Certificate of Analysis

 

Product Name: Etrasimod (APD334)
Catalog Number: M10226
CAS Number: 1206123-37-6

Physical and Chemical Properties
Formula: C26H26F3NO3
Molecular Weight: 457.48
Solubility: DMSO 25 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Etrasimod (APD334) Structure
Analytical Data
QC Standard: 98.94%
H-NMR: Consistent with structure
Product Information
Description: Etrasimod (APD334) is a specific and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor, with IC50 of 1.88 nM in CHO cells.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.