Certificate of Analysis
| Product Name: | ESI-08 |
| Catalog Number: | M29863 |
| CAS Number: | 301177-43-5 |
Physical and Chemical Properties
| Formula: | C20H23N3OS |
| Molecular Weight: | 353.48 |
| Form: | Solid |
| Solubility: | DMSO 100 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage: | 4°C, protect from light |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | ESI-08 is a potent and selective EPAC antagonist, which can completely inhibit both EPAC1 and EPAC2 (IC50 of 8.4 μM) activity. ESI-08 selectively blocks cAMP-induced EPAC activation, but does not inhibit cAMP-mediated PKA activation. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |