Certificate of Analysis

 

Product Name: Escin-IA
Catalog Number: M4566
CAS Number: 123748-68-5

Physical and Chemical Properties
Formula: C55H86O24
Molecular Weight: 1131.26
Form: Solid
Solubility: DMSO ≥ 60 mg/mL
Storage: 4°C, protect from light, dry, sealed
Chemical Structure: Escin-IA Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: Escin IA, a triterpenoid saponin isolated from horse chestnut, inhibits HIV-1 protease with IC50 value of 35 μM. Escin IA has anti-metastasis activity of triple negative breast cancer, and its mechanism includes down-regulation of LOXL expression and inhibition of epithelial mesenchymal transformation.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.