Certificate of Analysis
| Product Name: | Escin-IA |
| Catalog Number: | M4566 |
| CAS Number: | 123748-68-5 |
Physical and Chemical Properties
| Formula: | C55H86O24 |
| Molecular Weight: | 1131.26 |
| Form: | Solid |
| Solubility: | DMSO ≥ 60 mg/mL |
| Storage: | 4°C, protect from light, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Escin IA, a triterpenoid saponin isolated from horse chestnut, inhibits HIV-1 protease with IC50 value of 35 μM. Escin IA has anti-metastasis activity of triple negative breast cancer, and its mechanism includes down-regulation of LOXL expression and inhibition of epithelial mesenchymal transformation. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |