Certificate of Analysis

 

Product Name: Ertugliflozin L-pyroglutamic acid
Catalog Number: M14269
CAS Number: 1210344-83-4

Physical and Chemical Properties
Molecular Weight: 566
Solubility: DMSO ≥ 90 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Ertugliflozin L-pyroglutamic acid Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a potent, selective and orally active inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2), with an IC50 of 0.877 nM for h-SGLT2.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.