Certificate of Analysis

 

Product Name: Elobixibat hydrate
Catalog Number: M21416
CAS Number: 1633824-78-8

Physical and Chemical Properties
Formula: C36H47N3O8S2
Molecular Weight: 713.90
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Elobixibat hydrate Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Elobixibat hydrate is a potent bile acid transporter (IBAT) inhibitor with IC50 values of 0.53±0.17 nM (human IBAT), 0.13±0.03 nM (mouse IBAT), and 5.8±1.6 nM (canine IBAT). Elobixibat hydrate can be used in the study of chronic functional constipation (CIC) in the elderly.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.