Certificate of Analysis


Product Name: Elexacaftor (VX-445)
Catalog Number: M10162
CAS Number: 2216712-66-0

Physical and Chemical Properties
Formula: C26H34F3N7O4S
Molecular Weight: 597.65
Solubility: DMSO 100 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Elexacaftor (VX-445) Structure
Analytical Data
HPLC: Shows Min 99.5% purity
H-NMR: Consistent with structure
Product Information
Description: Elexacaftor (VX-445) is a next-generation modulator of cystic fibrosis transmembrane conductance regulator (CFTR).
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.