Certificate of Analysis

 

Product Name: EHT 1864 2HCl
Catalog Number: M6704
CAS Number: 754240-09-0

Physical and Chemical Properties
Formula: C25H27F3N2O4S.2HCl
Molecular Weight: 581.47
Solubility: Water ≥ 90 mg/mL; DMSO ≥ 30 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: EHT 1864 2HCl Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: EHT 1864 is a potent inhibitor of Rac family GTPases. EHT 1864 directly binds and impairs the ability of this small GTPase to engage critical downstream effectors required for growth transformation. The Kd values are 40, 50, 60, and 230 nM for Rac1, Rac1b, Rac2 and Rac3, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.