Certificate of Analysis
| Product Name: | EHNA hydrochloride |
| Catalog Number: | M6703 |
| CAS Number: | 58337-38-5 |
Physical and Chemical Properties
| Formula: | C14H23N5O.HCl |
| Molecular Weight: | 313.83 |
| Solubility: | Water 70 mg/mL; DMSO 50 mg/mL |
| Storage: | -20°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4 μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8 μM (human), 2 μM (porcine myocardium)). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |