Certificate of Analysis
| Product Name: | EGFR-IN-7 |
| Catalog Number: | M29467 |
| CAS Number: | 2267329-76-8 |
Physical and Chemical Properties
| Formula: | C32H41BrN9O2P |
| Molecular Weight: | 694.6 |
| Form: | Solid |
| Solubility: | DMSO 5 mg/mL (ultrasonic and warming and adjust pH to 5 with 0.1 M HCL and heat to 60°C) |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | EGFR-IN-7 is a potent, selective and orally active EGFR kinase inhibitor. EGFR-IN-7 has inhibitory effect for for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) with IC50 values of 7.92 nM and 0.218 nM, respectively. EGFR-IN-7 can be used for the research of various cancers. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |