Certificate of Analysis

 

Product Name: E7090 succinate 
Catalog Number: M28979
CAS Number: 1879965-80-6

Physical and Chemical Properties
Formula: C32H37N5O6.3/2C4H6O4
Molecular Weight: 764.82
Form: Solid
Solubility: DMSO 100 mg/mL (ultrasonic)
Storage: 4°C, dry, sealed
Chemical Structure: E7090 succinate  Structure
Analytical Data
QC Standard: ≥99.0%
H-NMR: Consistent with structure
Product Information
Description: E7090 succinate is an orally available, selective and potent inhibitor of FGFR1, FGFR2 and FGFR3 tyrosine kinase activities, with IC50 values of 0.71 nM, 0.50 nM, 1.2 nM, and 120 nM for FGFR1/2/3/4, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.