Certificate of Analysis
| Product Name: | DTHIB |
| Catalog Number: | M20805 |
| CAS Number: | 897326-30-6 |
Physical and Chemical Properties
| Formula: | C13H9ClFN3O3 |
| Molecular Weight: | 309.68 |
| Solubility: | DMSO 86 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| HPLC: | Shows Min >99% purity |
| H-NMR: | Consistent with structure |
Product Information
| Description: | DTHIB (Direct Targeted HSF1 InhiBitor) is a direct and selective inhibitor of heat shock factor 1 (HSF1) with Kd of 160 nM for DTHIB binding to the HSF1 DNA binding domain (DBD). DTHIB exhibits potently anticancer activities. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |