Certificate of Analysis

 

Product Name: Dovitinib lactate
Catalog Number: M14898
CAS Number: 692737-80-7

Physical and Chemical Properties
Molecular Weight: 482.51
Solubility: DMSO ≥ 30 mg/mL
Storage: 2-8°C, dry, sealed
Chemical Structure: Dovitinib lactate Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Dovitinib lactate (TKI258 lactate) is a multi-targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8/9, 10/13/8, 27/210 nM for FLT3, c-Kit, FGFR1/3, VEGFR1/2/3 and PDGFRα/β, respectively.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.