Certificate of Analysis

 

Product Name: Dovitinib (TKI-258) Dilactic Acid
Catalog Number: M5592
CAS Number: 852433-84-2

Physical and Chemical Properties
Formula: C21H21FN6O.2C3H6O3
Molecular Weight: 572.59
Solubility: 90 mg/mL in DMSO
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Dovitinib (TKI-258) Dilactic Acid Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.