Product Name: | Dolutegravir |
Catalog Number: | M3484 |
CAS Number: | 1051375-16-6 |
Formula: | C20H19F2N3O5 |
Molecular Weight: | 419.38 |
Solubility: | DMSO 60 mg/mL |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: | ![]() |
HPLC: | Shows Min >99% purity |
H-NMR: | Consistent with structure |
Description: | Dolutegravir (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM, modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |