Product Name: | DK419 |
Catalog Number: | M29240 |
CAS Number: | 2102672-22-8 |
Formula: | C16H8ClF6N3O |
Molecular Weight: | 407.7 |
Form: | Solid |
Solubility: | DMSO 83.33 mg/mL (ultrasonic) |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: |
QC Standard: | ≥99.0% |
H-NMR: | Consistent with structure |
Description: | DK419 is a potent and orally active Wnt/β-catenin signaling inhibitor, with an IC50 of 0.19 μM. DK419 reduces protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin and induces production of pAMPK. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |