Certificate of Analysis
| Product Name: | Dihydrexidine hydrochloride |
| Catalog Number: | M28278 |
| CAS Number: | 137417-08-4 |
Physical and Chemical Properties
| Formula: | C17H18ClNO2 |
| Molecular Weight: | 303.78 |
| Form: | Solid |
| Solubility: | DMSO 83.33 mg/mL (ultrasonic); Water 10 mg/mL (ultrasonic) |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Dihydrexidine hydrochloride (DAR-0100 hydrochloride) is a high potent, selective and full efficacy D1-like dopamine receptor (D1/D5) agonist, with an IC50 of 10 nM for D1 receptor. Dihydrexidine hydrochloride exhibits potent antiparkinsonian activity. Dihydrexidine hydrochloride can stimulate YAP phosphorylation. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |