Product Name: | Dehydrocostus-Lactone |
Catalog Number: | M4476 |
CAS Number: | 477-43-0 |
Formula: | C15H18O2 |
Molecular Weight: | 230.3 |
Solubility: | DMSO 40 mg/mL |
Storage: | 2-8°C, dry, sealed |
QC Standard: | >99.0% |
H-NMR: | Consistent with structure |
Description: | Dehydrocostus-lactone (DHE) is a natural sesquiterpene lactone, inhibits IKKβ activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation, and their DNA binding activity on COX-2 promoter. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |