Certificate of Analysis

 

Product Name: DCPIB
Catalog Number: M21042
CAS Number: 82749-70-0

Physical and Chemical Properties
Formula: C22H28Cl2O4
Molecular Weight: 427.36
Solubility: DMSO 85 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: DCPIB Structure
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: DCPIB is a specific and potent inhibitor of volume-regulated anion channels (VRAC). DCPIB potently inhibits several K2P channels with no voltage dependence, including TRESK, TASK1, and TASK3. DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.