Certificate of Analysis
| Product Name: | DBCO-(PEG)3-VC-PAB-MMAE |
| Catalog Number: | M49827 |
| CAS Number: | 2754384-60-4 |
Physical and Chemical Properties
| Formula: | C86H124N12O18 |
| Molecular Weight: | 1613.97 |
| Form: | Solid |
| Solubility: | DMSO 60 mg/mL |
| Storage: | -20°C |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | DBCO-(PEG)3-vc-PAB-MMAE is an active molecule coupler (drug-linker conjugate for ADC) consisting of auristatin E attached to a DBCO-(PEG)3-vc-PAB connector. It can be used for cancer research. In addition, DBCO-(PEG)3-vc-PAB-MMAE is a click chemistry that contains a DBCO moiety and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an Azide moiety. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |