Product Name: | DBCO-Maleimide |
Catalog Number: | M58138 |
CAS Number: | 1395786-30-7 |
Formula: | C25H21N3O4 |
Molecular Weight: | 427.45 |
Solubility: | DMSO 80 mg/mL |
Storage: | -20°C, sealed |
Chemical Structure: | ![]() |
QC Standard: | ≥95.0% |
H-NMR: | Consistent with structure |
Description: | DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |