Certificate of Analysis

 

Product Name: DBCO-Maleimide
Catalog Number: M58138
CAS Number: 1395786-30-7

Physical and Chemical Properties
Formula: C25H21N3O4
Molecular Weight: 427.45
Solubility: DMSO 80 mg/mL
Storage: -20°C, sealed
Chemical Structure: DBCO-Maleimide Structure
Analytical Data
QC Standard: ≥95.0%
H-NMR: Consistent with structure
Product Information
Description: DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.