Certificate of Analysis
| Product Name: | (D) PPA-1 TFA |
| Catalog Number: | M25528 |
| CAS Number: | 1620813-53-7 (free base) |
Physical and Chemical Properties
| Formula: | C72H99N20F3O23 |
| Molecular Weight: | 1669.67 |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Analytical Data
| QC Standard: | >98.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | (D) PPA-1 TFA is the first hydrolysisresistant D-peptide antagonists to target the PD-1/PD-L1 pathway. (D) PPA-1 could bind PD-L1 at an affinity of 0.51 μM in vitro. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |