Product Name: | CZ-48 |
Catalog Number: | M58990 |
CAS Number: | 1374663-29-2 |
Formula: | C11H14FN2O6PS |
Molecular Weight: | 352.28 |
Form: | Solid |
Solubility: | Water 100 mg/mL; DMSO 80 mg/mL |
Storage: | -20°C, sealed |
QC Standard: | ≥99.0% |
H-NMR: | Consistent with structure |
Description: | CZ-48 (Sulfo-ara-F-NMN) is a mimetic of nicotinamide mononucleotide (NMN). CZ-48 acts selectively, activating SARM1 but inhibiting CD38 (IC50 around 10 μM). CZ-48 induces intracellular cyclic ADP-ribose (cADPR) production. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |