Certificate of Analysis
| Product Name: | Cyclosporin D |
| Catalog Number: | M30409 |
| CAS Number: | 63775-96-2 |
Physical and Chemical Properties
| Formula: | C63H113N11O12 |
| Molecular Weight: | 1216.64 |
| Form: | Solid |
| Solubility: | DMSO 25 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage: | Store at ≤ -20°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal standard for quantification of Cyclosporin A. Cyclosporin A is a potent immunosuppressant agent, suppress T cell activation by inhibiting calcineurin and the calcineurin-dependent transcription factors nuclear factor of activated T cells (NFAc). |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |