Certificate of Analysis

 

Product Name: Cromakalim
Catalog Number: M6634
CAS Number: 94470-67-4

Physical and Chemical Properties
Formula: C16H18N2O3
Molecular Weight: 286.33
Solubility: DMSO 60 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Cromakalim Structure
Analytical Data
QC Standard: >99.0%
H-NMR: Consistent with structure
Product Information
Description: Cromakalim is a kir6 (KATP) channel opener. Cromakalim relaxes rabbit isolated portal vein with an IC50 value of 21 nM. Cromakalim is potent, orally active and hypotensive in vivo.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.