Certificate of Analysis

 

Product Name: Crinecerfont hydrochloride
Catalog Number: M54654
CAS Number: 321839-75-2

Physical and Chemical Properties
Formula: C27H29Cl2FN2OS
Molecular Weight: 519.50
Form: Solid
Solubility: DMSO 100 mg/mL
Storage: 4°C, protect from light, dry, sealed
Chemical Structure: Crinecerfont hydrochloride Structure
Analytical Data
QC Standard: >99.0%
H-NMR: Consistent with structure
Product Information
Description: Crinecerfont hydrochloride is a potent, orally active, nonpeptide CRF1 receptor antagonist for use in congenital adrenal hyperplasia (CAH) studies. In addition, Crinecerfont hydrochloride is a click chemistry. It contains an Alkyne moiety that undergoes a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Azide moiety.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.