Certificate of Analysis
| Product Name: | CPI-455 |
| Catalog Number: | M8937 |
| CAS Number: | 1628208-23-0 |
Physical and Chemical Properties
| Formula: | C16H14N4O |
| Molecular Weight: | 278.31 |
| Solubility: | DMSO 30 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | 99.89% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | CPI-455 is a potent and selective inhibitor of KDM5 demethylases which reduces survival of cancer cells, with a half-maximal inhibitory concentration (IC50) of 10 ± 1 nM for full-length KDM5A in enzymatic assays. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |